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Review on Feature Selection Techniques and the Impact of SVM for Cancer Classification using Gene Expression Profile

机译:特征选择技术及sVm对癌症影响的研究进展   使用基因表达谱进行分类

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摘要

The DNA microarray technology has modernized the approach of biology researchin such a way that scientists can now measure the expression levels ofthousands of genes simultaneously in a single experiment. Gene expressionprofiles, which represent the state of a cell at a molecular level, have greatpotential as a medical diagnosis tool. But compared to the number of genesinvolved, available training data sets generally have a fairly small samplesize for classification. These training data limitations constitute a challengeto certain classification methodologies. Feature selection techniques can beused to extract the marker genes which influence the classification accuracyeffectively by eliminating the un wanted noisy and redundant genes This paperpresents a review of feature selection techniques that have been employed inmicro array data based cancer classification and also the predominant role ofSVM for cancer classification.
机译:DNA微阵列技术已使生物学研究方法现代化,从而使科学家现在可以在单个实验中同时测量数千个基因的表达水平。在分子水平上代表细胞状态的基因表达谱作为医学诊断工具具有巨大的潜力。但与涉及的基因数量相比,可用的训练数据集通常具有相当小的样本量用于分类。这些训练数据的局限性对某些分类方法构成了挑战。特征选择技术可用于通过消除不需要的杂音和冗余基因来提取有效影响分类准确性的标记基因。本文介绍了基于微阵列数据的癌症分类中已采用的特征选择技术,以及SVM在癌症中的主要作用分类。

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